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It functions as a nucleotide exchange factor (NEF) for GRP78 and facilitates ER-associated protein degradation, particularly in response to immune stimulation, as detailed in a comprehensive review by Wang and colleagues (Wang et al., 2015)
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[DOI] [PubMed] [Google Scholar] 59.Rosa S.B., Caverzan A., Teixeira F.K., Lazzarotto F., Silveira J.A.G., Ferreira-Silva S.L., Abreu-Neto J., Margis R., Margis-Pinheiro M
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