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It is a widely used bioactive compound with substantial therapeutic and biological activity [155], including anti-inflammatory [246, 248], gut microbiota-regulating [139], anti-neuroinflammatory [141], and antioxidant effects[89], and is used to treat various diseases
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Indeed, a study has shown that treatment with ω-3 PUFAs remarkably attenuated increases in hippocampal malondialdehyde and 8-hydroxy-2′-deoxyguanosine levels as well as decreases in reduced glutathione (GSH) levels and the GSH-peroxidase activity induced by pentylenetetrazol kindling in young rat models [153]
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