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A summary of immune-modifying medication use is reported in Supplemental Table S1, Any-grade imAEs that led to discontinuation of study treatment occurred in 22 (5.7%) participants in the STRIDE arm and 10 (2.6%) participants in the durvalumab monotherapy arm
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476,477 This abnormal gliogenesis is linked to a deficit in Sonic hedgehog (Shh) signalling
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