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Biodistribution and therapeutic effects in orthotopic osteosarcoma mouse model Based on these promising findings, the biosafety of Ru(II)-OH, NP2, or NP4 at a doses of 2 mg Ru/kg was studied upon intravenous injection into the tail vein of healthy female mice on the days 1, 4, and 7
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Intramuscular injection of artemether was more neurotoxic than that of artesunate in a mouse model, suggesting differences in the optimal dosing of different derivatives (Nontprasert et al., 1998
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